FORMULATION AND CHARACTERIZATION OF ACECLOFENAC LOADED STARCH MICROSPHERE

Microspheres are a new category of novel drug delivery system which targets to increase the bioavailability and is formulated expediently obtain prolonged or controlled in body. Aceclofenac; non steroidal anti inflammatory drug, used treat hurting rheumatic conditions such as osteoarthritis, rheumatoid arthritis alkylosing spondylitis. It eases pain reduces inflammation at various sites. Aceclofenac acts by blocking effect chemical mediators called cyclo-oxygenase (COX) enzymes released inflamed regions. The aim this research was formulate loaded starch microspheres evaluate its vitro properties enhance aceclofenac tablet. were prepared using emulsion cross linking method. with polymer characterized, evaluated it found influence all parameters. showed great entrapment efficiency. In release polymeric formulations quite good.